How many pills of Mobosetinib should be taken a day and how many boxes can be used in a month?

Mobocertinib is an oral kinase inhibitor previously approved for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations that progress during or after platinum-based chemotherapy. This is a first-in-class oral therapy specifically designed to target EGFR exon 20 insertion mutations.

When moboxetinib is launched, it is available in the form of 40 mg capsules. The recommended dose is 160 mg (4 capsules), taken once daily with or without food. Currently, the specifications of each box of the original drug Moboxetinib (original drug Moboxetinib succinate) on the domestic market is 40mg*112 tablets. It is estimated that patients need to use about 1 box per month, provided that the patient does not interrupt or discontinue the drug due to adverse reactions and other factors. The size of each box of the Hong Kong version is 40mg*30 tablets, and it is estimated that patients need to use about 4 boxes a month.

The domestically marketed Mobosetiniboriginal drug has not yet been included in medical insurance. The price of the specification40 mg*112 pills per box is around 40,000 yuan, which is very expensive.The Hong Kong version of the original drug specification40mg*30 pills per box is priced at more than 7,000 yuan (the price may fluctuate due to exchange rates). Generic drugs of Mobotinib have also been put on the market for sale overseas. The drug ingredients are basically the same as those of the original drugs at home and abroad. For example, the production specifications of Laos Pharmaceutical Factory40mg*120 pills per boxThe pricemay be more than 4,000 yuan (the price may fluctuate due to the exchange rate), and the price is relatively cheap.