New anti-cancer drug: How to use mobosetinib, briefly understand its usage

Doctors will select patients with locally advanced or metastatic non-small cell lung cancer for mobocertinib/mobocertinib (Mobocertinib) treatment based on the presence of EGFR exon 20 insertion mutations. Before treatment, doctors also assess QTc and electrolytes to correct abnormalities in sodium, potassium, calcium and magnesium.

The recommended dose of mobosetinib is 160 mg taken orally once daily until disease progression or unacceptable toxicity occurs; take mobosetinib at the same time each day with or without food. Swallow mobosetinib capsules whole without opening, chewing, or dissolving the capsule contents. If you miss a dose by more than 6 hours, skip the dose and take the next dose at your regular time the next day. If you vomit after a dose, do not take another dose. Take the next dose as prescribed the next day.

If the patient experiences adverse reactions during treatment with mobosetinib, the doctor will adjust the drug dosage according to the severity of the condition; the first dose of mobosetinib can be reduced to orally once a day120mg; the second dose can be reduced to 80mg orally once a day.

Mobosetinib The original drug is currently on the market in China and has not yet been included in the medical insurance. SpecificationThe price of 40mg*112 pills per box is about 40,000 yuan, which is very expensive.The Hong Kong version of the original drug Specifications40mg*30 pills per box is priced at more than 7,000 yuan (the price may fluctuate due to exchange rates). Generic drugs of Mobotinib have also been put on the market for sale overseas. The drug ingredients are basically the same as those of the original drugs at home and abroad. For example, the production specifications of Laos Pharmaceutical Factory40mg*120 pills per boxThe pricemay be more than 4,000 yuan (the price may fluctuate due to the exchange rate), and the price is relatively cheap.