How does Sorafenib work?

Sorafenib is an oral cancer drug approved to treat 3 different types of cancer. In 2005, it was approved for the treatment of advanced kidney cancer. In 2007, it was approved for the treatment of unresectable liver cancer. 2103Year 11month, FDA approved sorafenib for the treatment of advanced (metastatic ) differentiated thyroid cancer. Sorafenib(Sorafenib)How does it work?

Sorafenib is classified as a vascular endothelial growth factor (VEGF) inhibitor and an angiogenesis inhibitor. It may also be called a multikinase inhibitor. Sorafenibworks by blocking certain proteins inside and on the surface of cancer cells, which may kill the cancer cell and prevent it from growing and spreading in the body. It also helps prevent the growth of new blood vessels, which help" Feeding”The growth of tumors(is called angiogenesis).

The most common adverse reactions of sorafenib (≥20%) are diarrhea, fatigue, infection, alopecia, hand-foot skin reaction, rash, weight loss, decreased appetite, nausea, gastrointestinal and abdominal pain, hypertension, and bleeding. Before taking sorafenib, tell your doctor and pharmacist ifpatient is allergic to sorafenib, any other medicine, or any of the ingredients in sorafenib tablets. If you have lung cancer and are receiving carboplatin (Paraplatin) and paclitaxel (Abraxane, Onxol, paclitaxel) )or gemcitabine(Gemzar) and cisplatin(Platinol)treatment, please inform your doctor. If you have lung cancer and are being treated with these drugs, your doctor may tell you not to take sorafenib. The retail price of Bangladesh Yaopin International Pharmaceutical 0.2g*120 tablets is about 700 yuan. Laos ASEAN Pharmaceutical Retail Prices0.2g*56Pieces500about yuan. IndiaNATCOPharmaceutical retail price0.2g*120tablets1000yuan. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.