Sorafenib is developed and produced by Bayer in Germany. Sorafenib is used to treat advanced renal cell carcinoma. Sorafenib is also used to treat hepatocellular carcinoma that cannot be treated with surgery and a certain type of thyroid cancer that has spread to other parts of the body and cannot be treated with radioactive iodine.
Before taking sorafenib, tell your doctor if a patient is allergic to sorafenib, any other medicine, or any ingredient in sorafenib tablets. If you have lung cancer and are receiving carboplatin (Paraplatin) and paclitaxel (Abraxane, Onxol, paclitaxel) )or gemcitabine(Gemzar) and cisplatin(Platinol)treatment, please inform your doctor. If you have lung cancer and are being treated with these drugs, your doctor may tell you not to take sorafenib. Tell your doctor about the prescription and over-the-counter drugs, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following:Certain drugs that treat cardiac arrhythmias, such as amiodarone(Nexterone,Pacerone), dofetilide(Tikosyn), dronedarone(Multaq) , procainamide, quinidine(Nuedexta) and sotalol(Betapace, Sorine, Sotylize); anticoagulant(Blood thinners), such as warfarin(Coumadin, Jan toven); carbamazepine(Equetro, Tegretol, span>Teril); dexamethasone; ibutilide(Corvert); irinotecan(Ca mptosar); neomycin; phenobarbital; phenytoin(phenytoin sodium, phenytoin sodium); Rifabutin(Mycobutin); or rifampicin(rifadine, rimatin). Many other drugs may also interact with sorafenib, so be sure to tell your doctor about all the drugs you are taking, even if they do not appear on this list. Tell your doctor about the herbal products you are taking, especially St. John's wort. Tell your doctor if you have or have ever had high blood pressure, bleeding problems, chest pain, heart problems, QTprolonged (cardiac Irregular rhythm, which may lead to fainting, unconsciousness, seizures, or sudden death), low levels of potassium, calcium, or magnesium in the blood, irregular heartbeat, heart failure, kidney problems other than kidney cancer, or liver problems other than liver cancer. If you are pregnant or plan to become pregnant, tell your doctor. Before starting treatment, a pregnancy test must be taken. If a woman is able to become pregnant, she must use effective contraception during treatment and for 6 months after the last dose. If the patient is a male and the female partner may become pregnant, effective contraception must be used during treatment and for 3 months after the last dose. If you become pregnant while taking sorafenib, tell your doctor immediately. Sorafenib may harm the fetus. Tell your doctor if you are breastfeeding or plan to breastfeed. Breastfeeding should not be done while taking sorafenib and for 2 weeks after the last dose. If you are having surgery, including dental surgery, tell your doctor that you are taking sorafenib. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.
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