How much does cabozantinib targeted therapy cost per month?

Cabozantinib (Cabozantinib) is used in two forms. The capsule form is clinically used to treat medullary thyroid cancer, and the tablet form is clinically used to treat renal cell carcinoma, hepatocellular carcinoma and differentiated thyroid cancer. Cabozantinib inhibits the following receptor tyrosine kinases: MET (hepatocyte growth factor receptor protein) and VEGFR, RET, GAS6 receptors (AXL, KIT), and Fms-like tyrosine kinase-3 (FLT 3).

When cabozantinib is provided in capsule form, the recommended dose is 140 mg once daily. Patients should not eat two hours before and one hour after taking the drug. Due to side effects, the dose may need to be reduced or temporarily stopped, especially during the first eight weeks of treatment. When cabozantinib is supplied as tablets, the recommended dose is 60 mg once daily; if severe or unacceptable side effects occur, dose reduction or temporary discontinuation of treatment may be necessary. Treatment continues as long as the patient benefits from it or the side effects become unacceptable.

The original drug Cabozantinib is not marketed in the country and therefore cannot be included in medical insurance. The original cabozantinib drug marketed overseas includes Japanese, Turkish and European versions. The price of tablets may be more than 30,000 yuan, and the price of capsule preparations may be more than 40,000 yuan (prices may fluctuate due to exchange rates). A patient's treatment for a month will cost about one box. There are also generic drugs produced in other countries overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs. For example, the price of pharmaceuticals produced by Bangladeshi pharmaceutical factories may be more than 2,000 yuan (the price may fluctuate due to the exchange rate), which is relatively cheap.