Is Sotoracib (AMG510) available in the country? What is the price?

Sotoracib (AMG510) is an anti-tumor targeted drug developed by Amgen in the United States. It was approved for marketing in the United States in 2021 on May . Sotoracib is indicated for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC). It is effective in treating cancer.

Currently, it has not been launched in the country, but clinical trials in China have been carried out, so the domestic launch of sotoracib is just around the corner. Currently, you can buy the original research version in Hong Kong, which costs more than 4 a month, which is quite stressful for ordinary families. There are also generic drugs of Sotoraxibu, and there are generic drugs that are officially marketed overseas, and the quality of the drugs is guaranteed. There are officially marketed versions of generic drugs in Laos and Bangladesh, which cost about 1 to 20000 a month. Patients can choose the medicine according to their actual situation.

Sotoracilbuis an inhibitor ofKRASG12Ca tumor-limiting, mutated, oncogenic form ofKRAS RAS gt pase. Sotorasiibforms an irreversible covalent bond with KRAS’s unique cysteineG12C, locking the protein in an inactive state and preventing downstream signaling without affecting wild-type KRAS. SotorasiibblocksKRAS signaling, inhibits cell growth and promotes apoptosisKRAS G12C tumor cell line. Because sotoracib is 89%bound to plasma proteins, its content in milk may be low. However, due to its potential toxicity to breastfed infants, it is recommended to discontinue breastfeeding during treatment with sotoraxib and within 1 week after the last dose. The retail price of Everest Pharmaceuticals in Bangladesh120mg56tablets4More than a thousand, the retail price of Zisika Pharmaceuticals in Bangladesh120mg56tablets3More than a thousand, the retail price of Laos Element Pharmaceuticals120mg56tablets4More than a thousand, the retail price of Lucius Pharmaceuticals in Laos120mg56tablets2000yuan. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.

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