New anti-cancer information: How many courses of treatment do mitotane usually take? Is the curative effect obvious?

Mitotane (Mitotane) has a toxic effect on a certain part of the adrenocortical cells, causing the death of these cells. This also reduces the amount of cortisol produced by the patient's body and changes the way the steroid is metabolized (processed) in the patient's body. Doctors may need to give patients oral steroids (such as hydrocortisone) to make up for this loss. The treatment cycle and dosage of mitotane will be adjusted according to the patient's needs. Generally speaking, treatment is often long-term and may take several months or even longer.

Overall, studies suggest that mitotane may benefit patients with advanced adrenocortical cancer by prolonging survival (more than 5 years in a few cases) and shrinking or stabilizing tumors in 20-30% of patients. It also reduces symptoms of the disease, especially in patients whose cancer produces high hormone levels. There is insufficient evidence to support its use as an add-on to other anticancer drugs. There is limited information on the use of mitotane in children, but overall, children taking mitotane remained disease-free for an average of 7 months.

The original drug of mitotane has been launched in China, but it has only been on the market for a short time, its purchase is very difficult, and it is not included in medical insurance. Mitotane marketed overseas The original drug has European and Turkish versions, specificationsThe price of 500mg*100 tablets per box may be more than 9,000 yuan (the price may fluctuate due to exchange rates). Mitotan generic drugs are also sold overseas, and their drug ingredients are basically the same as those of the original drug. For example, the specifications produced by Laos pharmaceutical factoriesThe price of 500mg*100 tablets per box may be more than 3,000 yuan (prices may fluctuate due to exchange rates).