What is the price of Eculizumab in 2024?

Eculizumab is an injection used to treat paroxysmal nocturnal hemoglobinuria (PNH; a type of anemia in which too many red blood cells are breaking down in the body, so there are not enough healthy cells to carry oxygen to various parts of the body). Eculizumab is also used to treat atypical hemolytic uremic syndrome (aHUS; a genetic disorder in which small blood clots form in the body and can cause damage to blood vessels, blood cells, kidneys and other parts of the body).

Eculizumab is also used to treat certain forms of myasthenia gravis (MG; a neurological disease that causes muscle weakness), and eculizumab is also used to treat neuromyelitis optica spectrum disorder (NMOSD; a neurological autoimmune disease that affects the nerves in the eyes and spinal cord). Eculizumab belongs to a group of drugs called monoclonal antibodies. It works by blocking parts of the immune system that can damage blood cells in people with PNH and lead to blood clots in people with aHUS. It also works by blocking activity in the immune system that could damage parts of the central nervous system in people with NMOSD or disrupt communication between nerves and muscles in people with MG.

The generic drug Eculizumab has been launched in China and is covered by medical insurance. It is only available for reimbursement to eligible patients. The specification is 300mg (30ml) and the price per box may be more than 3,000 yuan. It is understood that the price of each box of the original Eculizumab drug sold overseas is more than 6,000 US dollars (the price may fluctuate due to the exchange rate). The ingredients of the original drug sold at home and abroad are basically the same, and the price of the original drug is still relatively expensive. There are currently no generic versions of eculizumab available on the market.