What are the side effects of Osimertinib?

OsimertinibBelongs to the kinase inhibitor class of drugs. Osimertinib is suitable for patients with epidermal growth factor receptor (EGFR) exon19 deletion or exon21 Adjuvant therapy after tumor resection for patients with L858Rmutated non-small cell lung cancer (NSCLC), suitable for EGFRexon19 deletion or exon21 First-line treatment of patients with L858Rmutated metastatic non-small cell lung cancer. It is suitable for patients with metastatic EGFR T790M mutation-positive non-small cell lung cancer whose disease has progressed during or after treatment with EGFRtyrosine kinase inhibitors (TKI).

Osimertinib(Osimertinib)What are the side effects?

Common side effects of osimertinib include lymphopenia (63%), thrombocytopenia (46%), anemia (43%), diarrhea (41%), < span>Skin rash (34%), Neutropenia (27%), Hypermagnesemia (27%), Hyponatremia (26%), Dry skin (< /span>23%), Nail toxicity (22%), Fatigue (22%), Hypoglycemia (20%), Eye disease (18% ), Decreased appetite (18%), Cough (17%), Nausea (16%), Stomatitis (15%), Constipation ( 14% n>10%), Hypokalemia (9%), Lymphopenia, grade 3 or grade 4 (8.2%), Venous thromboembolism (7%), Pneumonia (4%), Interstitial lung disease/Pneumonia (3.3%)< /span>, QTcincrease from baseline 》60 milliseconds (2.7%) , grade 3 or grade 4 neutropenia (2.2%) , grade 3 or 4 hyponatremia (1.8%) , grade 3 or 4 pan> grade hypomagnesemia (1.8%), 3 grade or 4 grade hypokalemia (1.8%), 3 grade or 4 grade fatigue (1.8%), cardiomyopathy (1.4%), 3 grade or 4 grade diarrhea (1.1%), loss of appetite, 3 grade or 4 grade (1.1%) etc. Generic medicines cost several hundred yuan per box, and prices vary depending on the version. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.