Is pemetinib included in medical insurance?

Pemigatinib has been launched in China and has been included in medical insurance, which can reduce pressure on patients. Each locality has different medical insurance policies. Please consult the local area for specific reimbursement policies. Pemetinib is also available as a generic drug overseas. The officially marketed version costs about 1,000 yuan per box. For details, please consult domestic and overseas medical consulting agencies.

Pemetinib/Pemetinibis used to treat certain types of cholangiocarcinoma that have spread to nearby tissue or other parts of the body and cannot be removed with surgery. Pemetinib is also used in adults to treat certain types of bone marrow/lymphoid tumors. Pemetinib belongs to the kinase inhibitor class of drugs, which prevent cancer cells from multiplying by blocking the action of abnormal proteins, which can help stop or slow the spread of cancer cells.

After a single oral dose of 13.5 mg pemetinib, the median Tmax was 1.13 (0.50-6.00) hours. Steady state was reached within 4 days after repeated once-daily dosing, with a median drug accumulation ratio of 1.63 (range 0.63 to 3.28). Steady-state concentrations of pemetinib increased in a dose-proportional manner over the dose range of 1 to 20 mg, ranging from approximately 0.07 to 1.5 times the recommended dose. The average steady-state AUC and Cmax are 2620 nM x h (54% CV) and 236 nM, respectively. After a single oral dose of 13.5 mg pemetinib, the apparent volume of distribution was 235 L (60.8% CV). This is within the drug concentration range of 1 to 10 M in the test tube, and the serum protein binding rate of pemetinib 90.6%. Pemetinib is mainly metabolized in vitro by CYP3A4 enzyme. Its specific metabolic pathway and the metabolites produced have not been characterized. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to help you learn more about high-quality overseas drugs.

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