Latest reports! Price of pemetinib after launch in China

Pemigatinib will be released in2022year4month6 It was launched in China on . The retail price in domestic pharmacies is about 4.5mg*14 tablets29,800 yuan. If patients purchase domestically imported drugs, they can purchase them at local hospitals. There are original drugs and generic drugs overseas. The retail price of original drugs in pharmacies is about 13.5mg*14 tablets72,000 yuan. There are generic drugs in Laos, and they are all officially marketed generic drugs with government approval. The retail price of Lucius Pharmaceuticals in Laos is around 1000 yuan for 4.5mg*14 tablets.

Pemetinib is a cancer drug used to treat bile duct cancer, or cholangiocarcinoma, in adults when the cancer cells have an abnormal form of a receptor (target) on their surface called FGFR2. Pemetinib is used when the cancer has spread to other parts of the body or cannot be removed with surgery and has worsened after treatment with at least one previous cancer drug.

Pemetinibis a small molecule kinase inhibitor that exerts anti-tumor activity by inhibiting fibroblast growth factor receptors (FGFRs). 2Use integrated circuits50less than 2 At the wavelength of nM, pemetinib showed effective inhibition of FGFR1, FGFR2 and FGFR3. In mouse xenograft models of human tumors with alterations in FGFR1, FGFR2, or FGFR3, pemetinib demonstrated potent antitumor activity by inhibiting the growth of xenograft tumor models. It also showed efficacy in a patient-derived cholangiocarcinoma xenograft model expressing an oncogenic FGFR2 transformant-2β homolog (TRA2b TRA2b) fusion protein. Pemetinib also inhibits FGFR4 in vitro however its concentration ratio inhibits FGFR1,The concentrations of 2 and 3 are about 100 times higher. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to help you learn more about high-quality overseas drugs.