Is there a generic version of ivonib?

The original drug Ivosidenib (Ivosidenib) has been launched in many countries. It is understood that some countries overseas are currently producing generic drugs of Ivosidenib. Its pharmaceutical ingredients are basically the same as those of the original drug. It targets a specific gene mutation calledIDH1, which affects bone marrow. Generic drugs may have slight differences in production specifications and prices. Common manufacturers of generic drugs include Lucius Pharmaceuticals of Laos.

IDH1 mutations prevent young blood cells from developing into healthy adult blood cells, which can cause symptoms of acute myeloid leukemia (AML). Ivonib is for use only in adults with IDH1 mutations. Doctors test patients for this gene. Avosidenib is used to treat AML after other treatments have not worked or stopped working. It is also used to treat acute myeloid leukemia in adults 75 years and older who have newly been diagnosed with acute myeloid leukemia and who cannot be treated with certain chemotherapy because of other health problems. Avosidenib is also used to treat cholangiocarcinoma that has progressed or spread to other parts of the body (metastatic) after treatment with other drugs.

The original version of ivonib has been launched in China, but it is not covered by medical insurance. The price of domestically sold specifications0.25g*60 tablets per box is as high as 100,000 yuan, while the price of the original American version sold overseas is as high as more than 200,000 yuan per box (the price may fluctuate due to exchange rates). Generic drugs of Ivonib are also sold overseas. Their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 250mg*60 tablets produced by a Laos pharmaceutical factory may be more than 6,000 yuan per box (the price may fluctuate due to the exchange rate), and the price is relatively cheap.