Is Avonib expensive in Hong Kong?

Ivosidenib (Ivosidenib) is a cancer drug containing the active ingredientivosidenib, used to treat people with newly diagnosed acute myeloid leukemia (AML) For adults with locally advanced (has spread nearby) or metastatic (has spread to other parts of the body) biliary tract cancer, which are rare diseases, avosidenib is designated as an "orphan drug" (a drug for a rare disease).

To treat acute myeloid leukemia, ivosidenib can be combined with azacitidine, another cancer drug, which can only be used in patients whose cancer cells have the IDH1 R132 mutation (a specific mutation in the gene for a protein called isocitrate dehydrogenase 1 (IDH1)) and who cannot receive standard chemotherapy. To treat biliary tract cancer, ivosidenib can be used alone, and it can only be used in patients whose cancer has the IDH1 R132 mutation and who have received at least one previous systemic therapy (oral or injectable therapy).

The original version of ivonib has been launched in China, but it is not covered by medical insurance. The price of domestically sold specifications0.25g*60 tablets per box is as high as 100,000 yuan, while the price of the original American version sold overseas is as high as more than 200,000 yuan per box (the price may fluctuate due to exchange rates). Generic drugs of Ivonib are also sold overseas. Their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 250mg*60 tablets produced by a Laos pharmaceutical factory may be more than 6,000 yuan per box (the price may fluctuate due to the exchange rate), and the price is relatively cheap.