Is tucatinib/tucatinib available in China? Is it covered by medical insurance?

Tucatinib/TucatinibIt is not yet on the market in China and has not been included in medical insurance. Tucatinib is a kinase inhibitor that Tucatinib is used in combination with trastuzumab and capecitabine to treat patients with advanced unresectable or metastatic disease Adult patients with HER2-positive breast cancer, including patients with brain metastases who have received one or more prior anti-HER2-based regimens in the setting of metastasis. Tucatinibin combination with trastuzumab is indicated for the treatment of adult patients with RASwild-typeHER2 -positive unresectable or metastatic colorectal cancer that has progressed after treatment with fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy.

In vitro, Reversible inhibitor of CYPisoenzymes2C8 and 3A. Time-dependent inhibitor of CYP3A but not CYP isozymes1A2, 2B6, 2C9, 2C19 and 2D6 or uridine diphosphate glucuronosyltransferase (UGT)1a 1. P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP< /span>), but not the organic anion transporter (OAT) 1, pan>OAT3, organic cation transporter (OCT)1, OCT3, organic anion transporting polypeptide (OATP)1 B1、OATP1B3, multidrug and toxin efflux protein (MATE)1, MATE2K or a substrate of the bile salt export pump (BSEP).

The original drug is available in Hong Kong, and the retail price in pharmacies is about 150 mg 84 tablets 72,000 yuan. There are generic versions of this medicine in Bangladesh. The retail price of Everest Pharmaceuticals in Bangladesh is about 150 mg 30 tablets 6,000 yuan. The retail price of Ziska Pharmaceuticals in Bangladesh is around 4,500 yuan for 150 mg 30 tablets. If you want to get more high-quality information, you can contact Yaode, and Yaode will do its best to learn more about high-quality overseas drugs for you.