What are the side effects of Laos Element Pharmaceuticals Sotolasibu?

Sotoracib (AMG510) is a kinase inhibitor and the first drug targeting the KRAS G12C mutation. At present, Lao Element Pharmaceuticals has produced and marketed it. It has government approval and patients can choose the version themselves. Sotoracib is indicated for the treatment of adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC) who have received at least one prior systemic therapy, as determined by an FDA-approved test. What are the side effects of Laos Element Pharmaceuticals Sotorasibu?

The most common adverse reactions of sotoracib were diarrhea, musculoskeletal pain, nausea, fatigue, hepatotoxicity, and cough; the most common laboratory abnormalities were lymphopenia, decreased hemoglobin, increased AST, increased ALT, decreased calcium, increased alkaline phosphatase, increased urinary protein, and decreased sodium. 50%of patients treated with the drug experienced serious adverse reactions, including pneumonia, hepatotoxicity and diarrhea; the most common severe (grade 3 or above )Adverse reactions are ALTincrease, ASTincrease and diarrhea. Fatal adverse reactions include respiratory failure, pneumonia, cardiac arrest, heart failure, gastric ulcer, and pneumonia. 9% of patients permanently discontinued treatment due to adverse reactions; adverse reactions leading to permanent discontinuation of treatment included hepatotoxicity, ALT elevation, AST elevation, and drug-induced liver injury. The retail price of Bangladesh Everest Pharmaceuticals120mg56 tablets is priced from 4000 yuan to 5000 yuan. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.

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