Price comparison of ixazomib 4mg before and after medical insurance

Ixazomib is a reversible proteasome inhibitor that preferentially binds to the β5 subunit of the 20S proteasome and inhibits its chymotrypsin-like activity. 12 Based on in vitro studies, ixazomib induces apoptosis in multiple myeloma cell lines. It is also cytotoxic against myeloma cells that have relapsed after prior treatments, including bortezomib, lenalidomide, and dexamethasone.

Ixazomib should be used with dexamethasone and lenalidomide, which have specific dosing schedules within a cycle. Ixazomib and dexamethasone are given on days 1, 8, and 15; therefore, it is important to separate them because ixazomib should not be taken with food and dexamethasone should be taken with food.

IxazomibThe original drug has been launched in China and is included in Class B medical insurance. The common specifications are 4mg*1 capsule*3 capsules. The price of a common capsule preparation may be more than 10,000 yuan per box, which is relatively expensive. The price before and after medical insurance may be different due to the difference in local medical insurance reimbursement policies. The price after reimbursement will be cheaper than the original price.

The price of each box of the original ixazomib drug sold overseas is more than 10,000 US dollars (the price may fluctuate due to exchange rates). Ixazomib Generic drugs are also produced and sold overseas, and their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 4mg*3 tablets produced by a Laos pharmaceutical factory may be less than 1,000 yuan per box (the price may fluctuate due to the exchange rate), and the price is relatively cheap.