How much does a box of genuine Isazomi cost in 2024?

In November 2015, The U.S. Food and Drug Administration (FDA) approved ixazomib (Ixazomib, Ninlaro, Takeda Oncology) capsules combined with lenalidomide and dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma who have received at least one previous treatment. Ixazomib is the first FDA-approved oral proteasome inhibitor for this patient population and provides patients with a new oral treatment option to slow disease progression when other therapies have failed.

The safety and efficacy of ixazomib have been studied in an internationalPhase 3 double-blind clinical trial(TOURMALINE-MM1) pan>Confirmed in the study, more720 patients with relapsed and/or refractory multiple myeloma were randomly assigned to receive ixazomib plus lenalidomide and dexamethasone or placebo plus lenalidomide and dexamethasone. After the first prespecified interim analysis, progression-free survival (PFS) was significantly longer in the ixazomib plus lenalidomide and dexamethasone group compared with placebo plus lenalidomide and dexamethasone.

The original drug of Ixazomib has been launched in China and is included in Class B medical insurance. The price of common capsule preparations may be more than 10,000 yuan per box, which is relatively expensive. The price of the original drug of ixazomib sold overseas is more than 10,000 US dollars per box (the price may fluctuate due to the exchange rate). Ixazomib Generic drugs are also produced and sold overseas, and their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 4mg*3 tablets produced by a Laos pharmaceutical factory may be less than 1,000 yuan per box (the price may fluctuate due to the exchange rate), and the price is relatively cheap.