Anti-cancer drug: Dosage of ixazomib, simple understanding of how to use it

Ixazomib is a monoclonal antibody used with other drugs to treat multiple myeloma in people who have already received one other therapy. Before starting a new round of treatment, doctors will conduct relevant examinations on the patient, such as absolute neutrophil count, platelet count, non-hematological toxicity, etc. , and generally return to the patient's baseline status orGrade 1 or lower.

The recommended starting dose of ixazomib is4 mg orally administered once weekly on days 1, 8 and 15 of a 28-day treatment cycle. The recommended starting dose of lenalidomide is 25 mg administered daily on days 1 through 21 of a 28-day treatment cycle. The recommended starting dose of dexamethasone is 40 mg, administered on days 1, 8, 15, and 22 of a 28-day treatment cycle. Treatment should be continued until disease progression or unacceptable toxicity. Ixazomib should be taken once on the same day and at about the same time during the first three weeks of the four-week cycle, and should be taken at least one hour before or two hours after a meal. When initiating treatment, the importance of carefully following all dosage instructions should be discussed with the patient and the patient should be instructed to take the recommended dose as directed, as death has occurred from overdose.

The original drug of Ixazomib has been launched in China and is included in Class B medical insurance. The price of common capsule preparations may be more than 10,000 yuan per box, which is relatively expensive. The price of the original drug of ixazomib sold overseas is more than 10,000 US dollars per box (the price may fluctuate due to the exchange rate). Ixazomib Generic drugs are also produced and sold overseas, and their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 4mg*3 tablets produced by a Laos pharmaceutical factory may be less than 1,000 yuan per box (the price may fluctuate due to the exchange rate), and the price is relatively cheap.