What is the mechanism of action of Apelix? How does it work?

AlpelisibSold under the brand names Piqray and others, it is a drug used to treat certain types of breast cancer. ApelixFor use with fulvestrant. Apelix is an oral medicine marketed by Novartis. Common side effects include high blood sugar, kidney problems, diarrhea, rash, low blood cells, liver problems, pancreatitis, vomiting, and hair loss. Apelixis an α-specific PI3K inhibitor which was approved for medical use in the United States in 2019 May .

Apelvis works by blocking PIK3CA and is used to treat diseases in which specific genetic mutations occur in the PIK3CA gene. In breast cancer, mutations in the PIK3CA gene can lead to tumorigenesis. Apelvis can block PI3K, thereby reducing breast cancer growth. Compared with individual treatments, the combination of apelvis and fulvestrant has enhanced anti-tumor activity. In PIK3CAassociated overgrowth spectrum (PROS), mutations in the PIK3CA gene cause cells to grow and divide abnormally. This results in overgrowth and deformity that may affect different parts of the body, with symptoms varying widely across a range of clinically identifiable conditions. Vijoicetreats pro by blocking PI3K, thereby reducing cell growth and may improve pro symptoms or prevent them from getting worse. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.