Is Apelvis a chemotherapy drug?

Alpelisib is not a chemotherapy drug, it is a targeted drug. Apelvis is a kinase inhibitor used in combination with fulvestrant to treat hormone receptor (HR)-positive, human epidermal growth factor receptor2 (her Adult patients with 2)-negative, PIK3CA mutated advanced or metastatic breast cancer detected by an FDA-approved test after progression on an endocrine-based regimen.

Approximately40% are hormone receptor positive, human epidermal growth factor receptor2 (her Phosphatidylinositol3-kinase (PI3K) catalytic subunitp110α (pik 3c a) mutation occurs in patients with 2)-negative breast cancer. Apelix is a PI3K selective oral inhibitor that mainly has inhibitory activity against PIK3CA and has shown synergistic anti-tumor activity with endocrine therapy on hormone receptor-positive PIK3CA mutant breast cancer cells in preclinical and early clinical trials. ApelixThe combination with fulvestrant or aromatase inhibitors (such as letrozole) is safe and effective, and the toxicity is reversible. Although clinical activity was independent of PIK3CAmutation status, clinical improvement was primarily seen in a higher proportion of patients with PIK3CAmutated tumors. The retail price of the Indian version of the original medicine in pharmacies150mg28 is around three to four thousand per pill. The retail price of the European version in pharmacies is about 150mg56 tablets4 about 10,000 yuan. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.