What cancer does capmatinib treat?

Capmatinib (Capmatinib) is mainly used to treat non-small cell lung cancer (NSCLC), especially for patients with METexon 14 skipping mutation NSCLC. METExon 14Skipping mutant is a rare but biologically important mutation that involves a specific mutation in the MET gene in lung cancer cells, leading to abnormal activation of MET protein kinase.

METkinase is a receptor tyrosine kinase involved in cell growth and differentiation. When abnormally activated, it may promote the growth, differentiation and spread of cancer cells, especially in non-small cell lung cancer. Therefore, capmatinib, as a MET inhibitor, targets by specifically inhibiting the activity of MET protein kinase. METExon14skipping mutantNSCLC showed significant efficacy.

NSCLCis one of the main types of lung cancer, and there are relatively few patients with METexon14 skipping mutations, but their need for targeted therapy is very important. The application of capmatinib allows patients with this subtype to obtain more precise treatment, improve the effectiveness of treatment, prolong survival, and improve quality of life.

In general, the main application area of capmatinib is METexon14 non-small cell lung cancer with skipping mutations. Through its targeting effect, capmatinib provides an innovative and promising treatment option for lung cancer patients and represents an important advance in precision medicine in cancer treatment. With the deepening of scientific research, targeted therapy drugs such as capmatinib are expected to play a more important role in the treatment of lung cancer.

Capmatinib is not currently available in China, so patients cannot purchase it domestically and need to purchase it through overseas channels. Currently, there are Hong Kong version of original drugs and foreign original drugs and generic drugs. The price of Hong Kong version of original drugs is about 35,000 yuan. The overseas original drugs are mainly European version of original drugs, and the price is more than 50,000 yuan, so original drugs are still relatively expensive. Generic drugs on the market abroad are much cheaper, mainly Laos generic drugs, the price is around 3,000 to 4,000 yuan, and the ingredients of original drugs and generic drugs are basically the same.