How do palbociclib/palbociclib/palbociclib work?

Palbociclib is a cancer drug used to treat locally advanced (has spread to nearby) or metastatic (has spread to other parts of the body) breast cancer. Only when the cancer cell surface has certain hormone receptors(target) (HRpositive) and does not produce an abnormally large amount of HER2 called The receptor (HER[human epidermal growth factor]negative) can only be used palbocicillin.

Palmoxicillin blocks the activity of enzymes called cyclin-dependent kinases (CDK) 4 and 6, which play a key role in regulating the way cells grow and divide. In some cancers, including HR-positive breast cancer, the activity of CDK 4 and 6 is increased, which helps cancer cells multiply uncontrollably. By blocking CDK4 and CDK6, palbocicillin slowed the growth of HR-positive breast cancer cells.

Palbocicillin has been shown to extend patients' survival by an average of 6 to 10 months without worsening of their disease, which is considered to have clear clinical value. Regarding safety, the main risk is neutropenia, a well-known risk of many cancer drugs that is considered manageable. Therefore, the European Medicines Agency decided that the benefits of palbocicillin outweighed its risks and it could be authorized for use in the EU. Original drugs in Hong Kong cost around 1 million, while generic drugs cost around 7more than 7more than 4 more than 1,000 per box. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.