How much does Mobosetinib/Mobosetinib cost in Japan?

Mobocertinib/Mobocertinib (Mobocertinib) is manufactured by Japan's Takeda Pharmaceuticals), is a kinase inhibitor for the treatment of adults with non-small cell lung cancer (NSCLC): tumors that have spread to other parts of the body (metastatic) and cannot be removed by surgery, have an EGFR exon 20 insertion mutation, and whose disease worsens during or after platinum-based chemotherapy. Mobocertinibis available in capsule form, each capsule containing 40 mgMobocertinib.

The active ingredient of mobocertinibmobocertinib is a tyrosine kinase inhibitor (TKI), it is designed to specifically block the effect of EGFR receptors on the surface of cancer cells. In healthy cells, EGFR is activated only when new cells are needed, by promoting cell proliferation. In some cases of lung cancer, these receptors are overactive, allowing cancer cells to grow and divide uncontrollably. Mobosetinib prevents EGFR activation. Therefore it prevents the proliferation of cancer cells.

Mobosetinib The original drug has been launched in China, but it is not included in the medical insurance. The price of the common specification 40mg*112 pills per box is about 40,000 yuan, which is very high. The Hong Kong clinical version specification40mg*30 pills per box is priced at more than 7,000 yuan (the price may fluctuate due to the exchange rate). The price in Japan may be similar to this price. Generic drugs of Mobotinib have also been put on the market for sale overseas. Its pharmaceutical ingredients are basically the same as those of the original drugs at home and abroad. For example, the production specifications of Laos Pharmaceutical Factory 40mg*120 pills per box may be more than 4,000 yuan (the price may fluctuate due to the exchange rate), and the price is relatively cheap.