New anti-cancer drugs: clinical significance of mobosetinib/mobosetinib

The clinical significance of Mobocertinib/Mobocertinib (Mobocertinib) is to provide a new treatment option for patients with non-small cell lung cancer. Mobosetinib is an oral targeted therapy targeting epidermal growth factor receptor (EGFR) exon 20 insertion mutations. This mutation is rare in non-small cell lung cancer and carries a poor prognosis.

The launch of mobosetinib has filled the long-term gap in clinical treatment in this field, providing patients with new treatment options, and ushering in a new era of targeted treatment for non-small cell lung cancer with EGFR exon 20 insertion mutations. Clinical study results show that mobosetinib can improve the median progression-free survival (mPFS) to 7.3 months and the median overall survival (mOS) to 20.2 months in patients who have been treated with platinum-containing chemotherapy. This shows that moboxetinib can significantly prolong patient survival and improve patients' quality of life.

In addition, mobosetinib has a clear mechanism of action, is highly targeted, and has high efficacy and safety. The side effects of this drug are relatively mild. Common side effects include diarrhea, vomiting, nausea, loss of appetite, cough, dry skin, fatigue, itching, paronychia, rash, stomatitis, musculoskeletal pain, weight loss, etc.

Mobosetinib The original drug has been launched in China, but it is not included in the medical insurance. The price of the common specification 40mg*112 pills per box is about 40,000 yuan, which is very high. The Hong Kong clinical version specification 40mg*30 pills per box is priced at more than 7,000 yuan (the price may fluctuate due to exchange rates). Generic drugs of Mobotinib have also been put on the market for sale overseas. Its pharmaceutical ingredients are basically the same as those of the original drugs at home and abroad. For example, the production specifications of Laos Pharmaceutical Factory 40mg*120 pills per box may be more than 4,000 yuan (the price may fluctuate due to the exchange rate), and the price is relatively cheap.