Will Seleniso Health Insurance be included in medical insurance in 2024?

Selinexor (Selinexor) is an oral anticancer drug that belongs to a class of nuclear protein transport inhibitors. Its main ingredient is selinexor. The uniqueness of this drug is that it acts on the nuclear transport protein XPO1 (Exportin 1), thereby affecting protein transport between the nucleus and the cytoplasm, preventing specific proteins from entering the nucleus.

Seleniso is already on the market in China and has been included in medical insurance, but its price is quite expensive, about 10,000 to 20,000 yuan, making patients bear higher treatment costs. It is recommended to consult the local hospital pharmacy for specific prices and medical insurance reimbursement status. Different from the domestic market, Seleniso has two options: original drug and generic drug in the foreign market. The original drug is the American version of the original drug. Because of its higher research and development costs, the price is even more expensive, even as high as hundreds of thousands of yuan. In comparison, generic drugs are more affordable. Lao generic drugs are one of the relatively low-priced generic drugs, with prices ranging from 2,000 yuan to 4,000 yuan. Compared with original drugs, they are more affordable. The ingredients of original drugs and generic drugs are basically the same.

Selinesol’s main mechanism of action includes two aspects. First, it inhibits the normal transport of nuclear proteins by binding to Secondly, selinesol also interferes with the division and proliferation of cancer cells by regulating the cell cycle, thus preventing the growth of cancer.

The main area of application is the treatment of multiple myeloma (MM), especially in patients who are ineffective or intolerant to traditional treatments. Multiple myeloma is a type of leukemia in which plasma cells in the bone marrow abnormally proliferate, and selinesol has a significant therapeutic effect in this regard.