How long should I take Platinib? How long is the resistance time?

Platinib (pralsetinib) is an antineoplastic drug indicated for the treatment of adults with metastatic RETfusion-positive non-small cell lung cancer (NSCLC) and those requiring systemic therapy. Treatment of mutation-positive medullary thyroid carcinoma in adults and pediatric patients 12 years or older with advanced or metastatic RET and treatment requiring systemic therapy and radioactive iodine(Iodine-131)Refractory12 years old or 12 years old and above Advanced or metastatic RETfusion-positive thyroid cancer(suitable for this type of treatment) in adult and pediatric patients.

The package insert recommends a dose of 400 mg once daily, with treatment continued until disease progression or unacceptable toxicity occurs. The general resistance time of platinib is 8 to 11 months of action. The specific resistance time varies from person to person. Assess serum ALT and AST concentrations every 2 weeks during the first 3 months of treatment and monthly thereafter and as clinically indicated. 1weeks after initiating platinib treatment, monitor blood pressure at least monthly as clinically indicated. Skeletal and Dental Abnormalities Observed in Immature Animals Receiving Platinib,Monitor the growth plates of adolescents with open growth plates.

Closely monitor patients at risk for tumor lysis syndrome (eg, high tumor burden, rapidly growing tumors, renal dysfunction, dehydration). Monitor for signs of interstitial lung disease or pneumonia (such as dyspnea, cough, fever). Take orally once daily on an empty stomach (i.e., at least 2 hours after meals and 1 hours) before meals. If you miss a dose, take the missed dose as soon as you remember it that day, Take your next dose at the prescribed time. If you vomit after taking this dose, do not take additional doses to make up for the vomited dose. Take the next dose at the prescribed time. This medicine also has an overseas version. The retail price of Lucius Pharmaceuticals in Laos is more than 1,000 yuan. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.