Is there a generic version of Enasidenib?

The original drug Enasidenib (Enasidenib) is currently marketed and sold in many overseas countries. It is a drug for the treatment of acute myeloid leukemia (AML) in adult patients. It is understood that generic drugs of ensidipine are currently produced and sold. Its pharmaceutical ingredients are basically the same as those of the original drug. There may be slight differences in production specifications and prices. Common manufacturers of generic drugs include Ziska Pharmaceutical Factory in Bangladesh, Lucius Pharmaceutical Factory in Laos, etc.

Ensidipine is an oral drug that is an IDH2 (isocitrate dehydrogenase 2) inhibitor. It is mainly used to treat a specific type of acute myeloid leukemia (AML). Ensidipine inhibits the activity of the IDH2 mutant gene and blocks abnormal metabolic pathways, thereby reducing the proliferation and viability of malignant cells. This mutation causes myeloid stem cells to produce an abnormal metabolite, 2-hydroxyglutarate (2-HG). Ensidipine helps restore the normal hematopoietic process by inhibiting the activity of the IDH2 mutant gene and reducing the production of 2-HG. Ensidipine should only be used under the guidance of a physician, and its use must be tailored and monitored on an individual basis.

Encidipine research medicine is not currently on the market in China, so it cannot be included in medical insurance. The price of ensidipine plain medicine when it is launched overseas is very high, and the price of each box may be around 30,000 yuan (the price may fluctuate due to the exchange rate). Currently, there are relatively cheap generic ensidipine drugs sold overseas, such as the Specification50mg* produced by a Laos pharmaceutical factory. The price of 30 tablets per box may be more than 2,000 yuan (the price may fluctuate due to the exchange rate). For more information on overseas drug prices and specific information, please consult Yaode Medical Consultant.