Is Enasidenib Ensidipine?

Ensidipine(Enasidenib) and ensidipine are two different ways of saying the same drug. Enasidenib isits common English name, while ensidipine is another common way of expressing it. The product name sold overseas isIdhifa. Therefore, they refer to the same drug. As for which patients can be treated with ensidipine, as well as the sustained benefit and the optimal duration of treatment, doctors still need to make assessments and decisions based on the patient's situation.

Ensidipine is an anticancer drug primarily used to treat certain types of acute myeloid leukemia (AML), including relapsed or refractory patients with IDH2 gene mutations. It works by inhibiting the activity of the IDH2 enzyme, thereby reducing the accumulation of the abnormal metabolite 2-hydroxyvalerate (2-HG), thereby inhibiting the growth of leukemia cells. The shelf life of ensidipine varies from individual to individual. Based on clinical trial data, patients taking ensidipine may need to take it for several months or longer to see significant therapeutic effects.

Encidipine research medicine is not currently on the market in China, so it cannot be included in medical insurance. The price of ensidipine plain medicine when it is launched overseas is very high, and the price of each box may be around 30,000 yuan (the price may fluctuate due to the exchange rate). Currently, there are cheaper generic ensidipine drugs produced by other pharmaceutical companies overseas. For example, the price of Specification50mg*30 tablets produced by a Laos pharmaceutical factory may be more than 2,000 yuan per box (the price may fluctuate due to the exchange rate). Its pharmaceutical ingredients are basically the same as those of the original drugs sold abroad.