How long is the course of treatment with Seleniso? How many courses of treatment should be taken?

Selinexor is a selective inhibitor of nuclear export used in combination with dexamethasone to treat relapsed or refractory multiple myeloma(MM) in patients who have received at least 4 previously treated and whose disease is refractory to at least2 proteasome inhibitors, at least 2 immunomodulators, and antiCD38 monoclonal antibodies (Designated as an orphan drug by FDA for the treatment of this cancer). For the treatment of adult patients with multiple myeloma who have received at least one prior therapy, in combination with bortezomib and dexamethasone. For adult patients with relapsed or refractory diffuse largeB cell lymphoma(DLBCL)(Not otherwise stated, including DLBCL) caused by follicular lymphoma, are treated with at least 2 systemic therapies.

Currently, it is generally believed that the duration of each course of treatment is28 days, and selinesol is taken 80mg on the first and third days of each week. The treatment time of selinesol is generally 8< /span>—12 courses of treatment, ranging from 6 months to 1 years. Due to different personal circumstances, the actual treatment time needs to be determined according to the patient's specific situation and condition.

Monitor platelet counts throughout treatment and more frequently during the first 3 months of treatment. Monitor patients for signs and symptoms of bleeding and seek prompt evaluation. Monitor white blood cell counts throughout treatment and more frequently during the first 3 months of treatment. Monitor patients for signs and symptoms of co-infections and seek prompt evaluation. Monitor weight, nutritional and volume status throughout treatment and before treatment3Monitor more frequently every month. Monitor for diarrhea. Monitor sodium levels throughout treatment and more frequently during the first two months of treatment. Monitor for signs and symptoms of infection; evaluate and treat promptly. Monitor for dizziness and changes in mental status and institute appropriate fall prevention measures. Monitor for signs and symptoms of cataracts. The cost of each box of generic drugs is about three to four thousand yuan. For details, please consult overseas pharmaceutical institutions. If you want to get more high-quality information, you can contact YaoDe. YaoDe will do its best to learn more about high-quality overseas drugs for you.