What does canakinumab treat? Indications

Canakinumab(Canakinumab)Injection is used to treat cryopyrinrelated periodic syndrome (CAPS), including familial cold autoinflammatory syndrome (FCAS) and Markle-Wells syndrome (MWS). CAPSis a rare genetic immune system disease. Canakinumab injection is also used to treat tumor necrosis factor receptor-associated periodic syndrome (TRAPS) and hyperimmune globulinD syndrome (HIDSHIDSHIDS span>)/Mevalonate kinase deficiency (MKD) and familial Mediterranean fever (FMF). Canakinumab injection is also used to treat active Still's disease, including adult Still's disease (AOSD) and systemic juvenile idiopathic arthritis (SJIA). Canakinumab injection is also used to treat gout attacks in patients who are unable to receive or tolerate treatment or who have not responded to treatment with colchicine and NSAIDs. It is also used to treat gout attacks in patients who cannot receive repeated treatment with steroid drugs.

cap, TRAPS, HIDS/MKD and FMF are autoinflammatory periodic fever syndromes, and Still's disease is an autoinflammatory disorder. Autoinflammation occurs when the body produces too much of a chemical called interleukin-1β. This chemical causes inflammation (swelling), and people may experience fever, headache, rash, joint or muscle pain, or unusual fatigue or weakness. Canakinumab is an interleukin-1β receptor blocker. It helps prevent inflammation by keeping interleukin-1β working properly. The retail price in Turkish pharmacies is around 9,000 yuan per box. If you want to get more high-quality information, you can contact YaDE. YaDE will do its best to learn more about high-quality overseas drugs for you.