What is the price of adagrasib in 2024?

Adagrasib (Adagrasib) is used to treat metastatic (cancer that has spread) or locally advanced (cannot be removed with surgery) non-small cell lung cancer (NSCLC) in patients who have received at least one prior treatment and whose tumors have an abnormal KRAS G12C gene. Before patient takes this medicine, the doctor will examinethe patient. Adagrasiib is an antineoplastic drug (cancer drug) that works by interfering with the growth of cancer cells, which will eventually be eliminated.

Adagrasiib is aKRASG12C inhibitor with favorable properties, including long half-life (23 hours), dose-dependent pharmacokinetics and central nervous system (CNS) penetration. Relevant treatment-related adverse events (TRAEs) are generally mild to moderate in severity, initiated early in treatment, resolve rapidly with appropriate intervention, and result in low treatment discontinuation rates. Common TRAEs in clinical trials include gastrointestinal-related toxicity (diarrhea, nausea, and vomiting); hepatotoxicity (elevated alanine aminotransferase/aspartate aminotransferase) and fatigue, which can be controlled by adjusting dosage, diet, concomitant medications (such as antidiarrheal agents and antiemetics/antiemetics), and monitoring liver enzymes and electrolytes.

Sinceadagrasibthe original drug has not yet been launched in China, patients can only purchase adagrasib through overseas channels, and the U.S. original version of 200mg*180 tablets is priced at hundreds of thousands of yuan per box (the price may fluctuate due to exchange rates), which is very expensive. Currently, there are no generic drugs of adagrasib produced overseas. For more drug information and specific prices, please consult Yaode’s medical consultant.