How many days does one box of Serputinib/Serpatinib last?

Selpercatinib/Selpercatinib was first approved in the United States on May 8, 2020, for the treatment of adult patients with metastatic RET fusion-positive non-small cell lung cancer, Adult and pediatric patients ≥12 years of age with advanced or metastatic RET-mutant medullary thyroid cancer requiring systemic therapy and adult and pediatric patients ≥2 years of age with advanced or metastatic RET fusion-positive thyroid cancer requiring systemic therapy that is radioactive iodine refractory (if radioactive iodine is applicable).

Selpercatinib is available in capsule form containing 40 or 80 mg of selpercatinib. This medication is available by prescription only, and treatment should be initiated and supervised by a physician experienced in cancer treatment. The dose of seputinib is 160 mg twice daily, with the dose reduced to 120 mg twice daily for patients weighing less than 50 kg. Treatment with seputinib can continue until it stops working or the patient develops serious side effects.

Up to now, the original drug is sold in China under the name of Seputinib, but it is not covered by medical insurance. The price of each box of 80mg*56 tablets may be more than 10,000 yuan. It is estimated that one box can be used by patients for half a month (15 days). There are European and American versions of the original drugs sold overseas, with the price of each box ranging from 20,000 to more than 100,000 yuan (prices may fluctuate due to exchange rates). Generic drugs of Seputinib have also been put on the market for sale overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 40mg*120 capsules produced by a Laos pharmaceutical factory is more than RMB 4,000 per box (the price may fluctuate due to exchange rates).