Where to buy serputinib/serpatinib

Selpercatinib/Selpercatinib was approved in the United States in May 2020 for the treatment of adult patients with metastatic RET fusion-positive non-small cell lung cancer who have advanced or Adult and pediatric patients ≥12 years of age with metastatic RET-mutant medullary thyroid cancer requiring systemic therapy, and adult and pediatric patients ≥12 years of age with advanced or metastatic RET fusion-positive thyroid cancer requiring systemic therapy that is refractory to radioactive iodine (if radioactive iodine is appropriate). The recommended dose of this drug is 120 mg (for patients weighing <50 kg) or 160 mg (for patients weighing ≥50 kg) orally twice daily (≈12 h) until disease progression or unacceptable toxicity. Adverse reactions caused by seputinib include dry mouth, diarrhea, constipation, hypertension, fatigue, edema, and rash.

Up to now, the original drug is sold in China under the name Seputinib, but it is not covered by medical insurance. The price of each box of 80mg*56 tablets may be more than RMB 10,000. This drug may be sold in domestic hospitals or pharmacies. There are European and American versions of the original drugs sold overseas, with the price of each box ranging from 20,000 to more than 100,000 yuan (prices may fluctuate due to exchange rates). Generic drugs of Seputinib have also been put on the market for sale overseas, and their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 40mg*120 capsules produced by a Laos pharmaceutical factory is more than RMB 4,000 per box (the price may fluctuate due to exchange rates). For more overseas drug information and specific prices, please consult Yaode Medical Consultant.