How effective is the generic version of serputinib/serpatinib compared with the original drug?

Selpercatinib/Selpercatinib(Selpercatinib) is a targeted therapy drug targeting specific gene mutations. The original drug has shown significant efficacy in clinical trials for patients with multiple types of cancer with RET gene fusions or mutations,Such as non-small cell lung cancer, thyroid cancer, etc.. Original drugs are usually launched after long-term research and development, clinical trials and regulatory approval. However, as drug patents expire and market demand increases, generic drugs of Seputinibare gradually entering the market.

In some countries and regions, generic drugs need to undergo strict regulatory approval to ensure their consistency with the original drugs in terms of active ingredients, manufacturing processes, quality control, etc., to ensure their safety and effectiveness. In addition, some studies have shown that in some cases, there is no significant difference in clinical efficacy between generic drugs and brand-name drugs. Seputinib is also available overseasSeputinibGeneric drugs are on the market for sale, and their drug ingredients are basically the same as those of the original drugs sold domestically and abroad.Common generic drug manufacturers include BangladeshEverest Pharmaceutical Factory, Laos Lucius Pharmaceutical Factory, etc.

Up to now, the original drug is sold in China as Seputinib, but it is not included in medical insurance. The price of each box of specifications80mg*56 capsules may be more than 10,000 yuan. There are European and American versions of the original drugs sold overseas, with the price of each box ranging from 20,000 to more than 100,000 yuan (prices may fluctuate due to exchange rates). The generic Seputinib produced by Lucius Pharmaceutical Factory in Laos and sold overseas is priced at more than RMB 4,000 per box of 40mg*120 pills (the price may fluctuate due to exchange rates). For more overseas drug information and specific prices, please consult Yaode Medical Consultant.