What is the trade name of Pemetinib/Pemetinib?

Pemigatinib/Pemigatinib is marketed as Pemazyre in overseas and other regions Sold under the trade name Dabotan, and domestically sold under the trade name Dabotan, it is an anticancer drug for the treatment of cholangiocarcinoma, developed by Incyte, for the treatment of adults with relapsed or refractory myeloid/lymphoid tumors with fibroblast growth factor receptor 1 (FGFR1) rearrangements. In August 2022, the U.S. Food and Drug Administration (FDA) also approved pemetinib for adult patients with relapsed or refractory myeloid/lymphoid neoplasms (MLN) with FGFR1 rearrangements.

Pemetinib belongs to a group of drugs called protein kinase inhibitors. It works by blocking enzymes called protein kinases, specifically those that are receptors (targets) for fibroblast growth factor receptors (FGFRs). FGFRs have attracted attention as potential therapeutic targets in selected cancers because FGFR gene alterations have been observed in a variety of cancers, and fibroblast growth factor receptors are present on the surface of cancer cells and are associated with the growth and spread of cancer cells. By blocking tyrosine kinases in FGFRs, pemetinib has the potential to reduce the growth and spread of cancer.

The original drug of pemetinib has been launched in China. Due to its short time on the market, it has not yet entered the scope of medical insurance. Specification4.5mg*14 tablets per box may cost around 3about 10,000 yuan,Expensive. pemetinib original drug specifications13.5mg*14 tablets per box may be 7about 10,000 yuan (the price may fluctuate due to the exchange rate). Pemetinib is also produced in other countries overseasPemetinibGeneric drugs, such as those produced by Laos pharmaceutical factoriesSpecifications4.5mg*14 tabletsThe price of each box may be More than 1,000RMB (the price may fluctuate due to the exchange rate), The price is relatively cheap, and the pharmaceutical ingredients of generic drugs are the same as those in the country, The pharmaceutical ingredients of the original research drugs are basically the same.