How much does a box of crizotinib cost in 2024? Will medical insurance reimburse it?

Crizotinib (Crizotinib) is an anti-cancer drug used to treat non-small cell lung cancer (NSCLC), anaplastic large cell lymphoma (ALCL), and inflammatory myofibroblastic tumor (IMT). The trade name is Xalkori. As an inhibitor of ALK (anaplastic lymphoma kinase) and ROS 1 (c-ROS oncogene 1), it mainly targets kinases such as ALK, c-Met, ROS1 and RON. It inhibits the activity of these kinases, thereby blocking tumor cell proliferation and survival signals. In clinical trials, crizotinib has been shown to have significant inhibitory effects on tumor cells expressing specific fusion proteins.

The price of the original drug Crizotinib is usually relatively high. It is sold in China as Crizotinib capsules (XALKORI) and covered by medical insurance. There are two specifications of the drug: 250mg*60 capsules and 200mg*60 capsules. The price of each box may be more than RMB 10,000. Patients who meet the indications can use the national medical insurance for reimbursement. The price of each box of crizotinib original drug sold overseas may be more than RMB 10,000 (the price may fluctuate due to exchange rates).

Generic drugs are drugs produced by other pharmaceutical companies according to the standards and specifications of the original drug after the patent of the original drug expires. There are already cheaper generic crizotinib drugs overseas, and their drug ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of 250mg*60 tablets produced by pharmaceutical factories in Bangladesh and Laos may be around 2,000 yuan per box (the price may fluctuate due to exchange rates). For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.