What are the side effects of Eltrombopag/Eltrombopag?

Eltrombopag/Eltrombopag is a drug used to treat a specific type of thrombocytopenia (ITP). It is used to treat idiopathic thrombocytopenia caused by an overactive immune system and thrombocytopenia associated with chronic liver disease. This medication stimulates the bone marrow to produce more platelets to increase platelet counts and help prevent bleeding.

In clinical studies of eltrombopag, the most common side effects in adult patients with thrombocytopenia were nausea, diarrhea, and abnormal blood levels of certain liver enzymes. The most serious side effects are bleeding, liver problems, and thromboembolic complications; the most common side effects in pediatric patients include nose and throat infections, cough, fever, abdominal or mouth and throat pain, toothache, and runny nose. The most common side effects in people with severe aplastic anemia include headache, dizziness, cough, pain in the abdomen or mouth and throat, nausea, diarrhea, joint pain, pain in the extremities, fatigue, fever, and abnormal blood levels of certain liver enzymes.

In patients with chronic hepatitis C-related thrombocytopenia receiving interferon and eltrombopag, the most common side effects include headache, anemia, decreased appetite, cough, nausea, diarrhea, high bilirubin levels in the blood, hair loss, itching, muscle pain, fever, fatigue, influenza-like illness, weakness, chills, and swelling; serious side effects are liver problems and thromboembolic complications.

After eltrombopag was marketed, adverse events including hyperpigmentation and yellowing of the skin also occurred. If a patient experiences adverse reactions after taking eltrombopag, the use of the drug should be adjusted under the guidance of a doctor.