How many tablets of Eltrombopag/Eltrombopag should be taken at a time?

Eltrombopag/ Eltrombopag is a drug that helps the body produce blood cells, mainly platelets. Platelets are important for blood clotting inthe body. This medicine is used to treat immune thrombocytopenia (ITP) and some patients with aplastic anemia. This medication is available as 12.5 mg, 25 mg, 50 mg, and 75 mg oral tablets.

According to the prescribing information of eltrombopag, the dosage for patients with persistent or chronic immune immune thrombocytopenia is as follows. The dosage of eltrombopag for children aged 1 to 5 years is 25 mg once daily (one 25 mg tablet );); patients with ITP and mild, moderate, or severe hepatic impairment (Child-Pugh For patients in categories A, B, and C), the starting dose is 25 mg once daily (one 25 mg tablet ). For patients with ITP of East Asian/Southeast Asian ancestry, start eltrombopag at a dose of 25 mg once daily (one 25 mg tablet); for patients with ITP and mild, moderate, or severe hepatic impairment, start eltrombopag at a dose of 12.5 mg once daily (one 1 2.5 mg tablet).

First-line patients with severe aplastic anemia should be treated with eltrombopag in addition to standard immunosuppressive therapy. Pediatric patients aged 2 to 5 years old should use eltrombopag at a dose of 2.5 mg/kg (tablets should be calculated according to body weight); pediatric patients aged 6 to 11 years old should use eltrombopag. 75mg (one 75mg tablet); The dose for patients 12 years and older is 150mg (two 75mg tablets or other ) once daily for 6 months. The first-line treatment dose is reduced by 50% for patients with severe AA of East Asian/Southeast Asian ancestry or patients with mild, moderate, or severe hepatic impairment.

For refractory severe aplastic anemia, the initial dose of eltrombopag for patients is 50 mg once daily (one 50 mg tablet ); for severe cases of East Asian/Southeast Asian ancestry The initial dose for AA patients or patients with mild, moderate, or severe hepatic impairment is 25 mg (one 25 mg tablet ) once daily; thereafter, the dose is adjusted in 50 mg increments every 2 weeks to achieve a platelet count ≥50*109/L. Do not exceed daily dose of 150mg.

Therefore, the specific dosage of eltrombopag should be individually assessed and determined by a doctor based on the patient's condition, age, weight and other factors. Before use, please be sure to read the drug instructions carefully and strictly follow the doctor's prescriptions and recommendations. Do not change the dosage or stop taking the medicine on your own, as this may affect the therapeutic effect or cause adverse reactions.