The Spring of Generic Drugs: Market Analysis Behind the Price Reduction of Generic Drugs of Sotorasibu

Sotorasib (Sotorasib) is a RAS GTPase family inhibitor and a KRASG12C inhibitor, developed by Amgen for the treatment of solid tumors with KRAS mutations, including non-small cell lung cancer (NSCLC) and colorectal cancer. In May 2021, sotorasiib received accelerated approval from the U.S. Food and Drug Administration (FDA) for the treatment of adult patients with KRAS G12C-mutant locally advanced or metastatic non-small cell lung cancer determined by an FDA-approved test who have received at least one prior systemic therapy.

Sotoracib is not currently on the market in China, and the price of the original drug listed in other regions is relatively expensive. The specifications of the original versionsotoracib and are available in Hong Kong, China. The price of 120mg*240 tablets is around RMB 80,000, and the European original research version The price of 120mg*240 tablets is more than RMB 40,000 (the price may fluctuate due to the exchange rate). The high cost of treatment has become an insurmountable obstacle for some patients to obtain treatment.

Against this background, the emergence of the generic drug sotoraxib, which provides similar therapeutic effects to the original drug at a more affordable price, has become a new treatment option for more and more patients. Compared with the traditional original drug, the therapeutic effect of generic sotoraxibu is not inferior. Through strict clinical trials and quality control, generic drugs ensure similarity with the original drugs in terms of active ingredients, dosage, safety and efficacy. This means that when patients use generic sotoraxib, they can obtain treatment effects comparable to those of the original drug without having to bear excessive treatment costs.

Common manufacturers of sotolasibu generic drugs include Laos Lucius, Daxiong Pharmaceutical, Bangladesh Everest Pharmaceutical, etc. Take Laos Lucius Pharmaceutical Factory as an example, the specifications they produce12 The price of 0mg*56 tablets per box is more than one thousand RMB, while the price of Daxiong Pharmaceuticals per box is more than two thousand RMB (the price may fluctuate due to the exchange rate). For more information on overseas drug prices and related information, please consult Yaode Medical Consultants.