How much does trifluridine and tipiracil (Lansifer) take per month and how much does it cost per month?

Trifluridine (Lonsurf) is a medicine used to treat adults with colorectal cancer (large bowel cancer) and metastatic (has spread to other parts of the body) stomach cancer. It is mainly used in people who have had or cannot receive other treatments for cancer. It can be used in combination with bevacizumab, another cancer drug, to treat colorectal cancer. Trifluridine and tipiracil are available in tablet form containing 15 mg of trifluridine and 6.14 mg of tipiracil, equivalent to 7.065 mg of tipiracil hydrochloride, or 20 mg of trifluridine and 8.19 mg of tipiracil, equivalent to 9.420 mg of tipiracil hydrochloride.

The dosage of trifluridine and tipiracil in the treatment of colorectal cancer and gastric cancer is determined according to the specific conditions of each patient. The usual standard dose is35mg/m^2 (calculated based on the trifluridine component), up to 80mg/dose, taken twice a day, from day 1 to day 5 and day 8 to day 12 of each 28-day cycle. This treatment cycle constitutes a cycle. However, the actual dosage should be determined by the doctor based on the patient's condition and physical condition.

The original drug of trifluridine and tipiracil is already on the market but is not covered by medical insurance. The price per box may be around around RMB 6,000, and the price per box of the Hong Kong version may be more than RMB 10,000. The Japanese version of trifluridine tipiracil listed overseas, specifications 20mg*20 tablets per box, may cost more than 5,000 yuan (the price may fluctuate due to exchange rates). There are also cheaper generic versions of trifluridine tipiracil tablets available for sale overseas. Their pharmaceutical ingredients are basically the same as those of the original drugs sold domestically and abroad. For example, the price of each box produced by an Indian pharmaceutical factory may be more than more than 1,000 yuan (the price may fluctuate due to exchange rates).