Entrectinib capsules (Luo Shengquan, Entrectinib) Chinese detailed instructions

1. Drug name

Drug name : Entrectinib Capsules

Common name: entrectinib

English name:Entrectinib Capsules

2. Ingredients

Each capsule contains the active ingredient entrectinib. Other ingredients may include capsule shells and fillers. Please refer to the drug package insert for detailed ingredients.

3. Indications

Enrectinib capsules are suitable for the treatment of the following types of cancer:

1.ROS1positive non-small cell lung cancer (NSCLC)

2.ALKpositive non-small cell lung cancer (NSCLC)

3.NTRKGene fusion tumors

4.Other solid tumors, such as gastrointestinal stromal tumor (GIST), melanoma (Melanoma), etc.

4. Usage and Dosage

1.Please use this medicine under the guidance of a doctor and strictly follow the doctor's instructions.

2.The generally recommended dosage is 600 mg orally once a day, each time, can be taken with or after meals.

3.The dose will be adjusted according to the patient's specific situation and condition. Do not change the dose or stop using it on your own.

4.If you forget to take a dose, refill it as soon as possible, but do not take a double dose too close to the time of your next dose.

5. Taboo

1.It is forbidden for those who are allergic to this product.

2.Contraindicated for pregnant and lactating women.

3.It should be used with caution or prohibited in patients with cardiovascular disease, severe liver damage, and severe renal damage.

6. Things to note

1.During the use of this medicine, relevant examinations should be carried out regularly, including blood routine, liver function, kidney function, etc.

2.If serious adverse reactions occur, such as difficulty breathing, chest tightness, rash, etc., you should stop taking the medicine immediately and seek medical treatment.

3.During the period of using this medicine, you should avoid drinking alcohol, smoking and taking other drugs, especially other anti-cancer drugs, to avoid drug interactions.

4.Pregnant women, lactating women and those planning pregnancy should avoid contact with this product.

7. Adverse reactions

1.Common adverse reactions include nausea, vomiting, diarrhea, fatigue and other gastrointestinal reactions and systemic reactions.

2.Possible serious adverse reactions include arrhythmia, liver function damage, interstitial lung disease, etc. If the above symptoms occur, you should seek medical treatment in time.

8. Drug interactions

1.Before using this medicine, tell your doctor about all the medicines you are taking, including prescription drugs, over-the-counter drugs, and supplements.

2.This drug may interact with other drugs, especially other anti-cancer drugs, such as paclitaxel, cisplatin, etc., which may increase the risk of adverse reactions.

9. Storage conditions

1.Please store this medicine in a cool, dry place away from direct sunlight.

2.Store out of reach of children.

10. Packaging specifications

Each bottle contains several capsules. Please refer to the instructions on the drug packaging for specific packaging specifications.

11. Manufacturer

Roche Pharmaceuticals (Roche)

12. Listing and price

Entrectinib is now available in China and included in the medical insurance system, and patients can purchase it domestically. However, it is quite expensive, costing about 20,000 yuan. For specific price information and medical insurance reimbursement details, patients are advised to consult their local hospital pharmacy for accurate information. In comparison, the price of foreign generic entrectinib drugs is relatively affordable, especially the generic drugs produced in Laos, which only cost about one to two thousand yuan. It is worth mentioning that the ingredients of these generic drugs are basically the same as those of the original drugs. Therefore, patients can choose a suitable treatment plan based on their own financial situation and doctor’s recommendations.

The above is the detailed instructions for Entrectinib Capsules (Luo Shengquan). If you have any questions or discomfort, please consult your doctor or pharmacist.