What is the latest price of obeticholic acid in 2024?

Obeticholic acid is a synthetic derivative of the endogenous major bile acid chenodeoxycholic acid. Chenodeoxycholic acid is mainly used to treat liver and bile duct diseases. Its efficacy as an anticholestasis and antihepatotoxic agent is well established. Obeticholic acid is currently only approved by the U.S. Food and Drug Administration (FDA) for the treatment of primary cholangitis (PBC), a disease characterized by the progressive destruction of small intrahepatic bile ducts by inflammatory cells. Obeticholic acid is approved in combination with ursodeoxycholic acid (UDCA) in patients who have had an inadequate biochemical response to UDCA monotherapy for more than 1 year. It is also approved as monotherapy in patients with primary cholangitis who cannot tolerate ursodeoxycholic acid, both based on reducing alkaline phosphatase (ALP) levels.

It is understood that obeticholic acid has not yet been approved for marketing in China, so it cannot be included in medical insurance, and its domestic price is not known. Obeticholic acid Original drugs currently on the market overseas, common specifications are5mg*30 tablets, 10mg*30 tablets, the price of each box may be more than 9,000 US dollars (the price may fluctuate due to the exchange rate), the price of the original drug is still relatively expensive. Generic drugs of obeticholic acid are already on the market for sale overseas, and their pharmaceutical ingredients are basically the same as those of the original drug. Common manufacturers include Laos ASEAN Pharmaceuticals, Bangladesh Beacon Pharmaceutical, etc. The price per box ranges from a few hundred to 1,000 yuan (the price may fluctuate due to the exchange rate). Compared with the price of the original drug, it is relatively cheap. For more drug information and specific prices, please consult Yaode Medical Consultant.