Is there a generic version of Apelix?

The original drug Alpelisib (Alpelisib) is currently marketed and sold in many overseas countries. It is a drug for the treatment of adult patients with certain mutations of advanced or metastatic breast cancer. According to the latest overseas news, generic drugs of Apelvis are currently produced and sold. Its pharmaceutical ingredients are basically the same as those of the original drug. There may be slight differences in production specifications and prices. Common manufacturers of generic drugs include Laos Lucius Pharmaceutical Factory, etc. SpecificationsThe price of 150mg*28 tablets per box may be more than 2,000 yuan (price may fluctuate due to exchange rate effects).

Apelvis belongs to the class of phosphoinositide 3-kinase (PI3K) inhibitors and is indicated for menopausal men and women with HR-negative, HER2-negative breast cancer that has progressed or metastasized to other organs in the body. Apelixcan be used with fulvestrant (Faslodex) to help treat breast cancer that has spread to nearby tissue or other parts of the body. Apelix’s main ingredient is piqray, which helps prevent cancer cells from spreading in the body by inhibiting the signals that cause cancer cells to multiply.

Apellis is available as film-coated tablets in strengths of 50 mg, 150 mg or 250 mg. In general, steady-state plasma concentrations of apelvis are achieved approximately 3 days after dosing. According to studies, apelvis is moderately bound to plasma proteins. Apelvis is evenly distributed between plasma and red blood cells, with an average blood to plasma (in vitro) ratio of approximately 1.03. At steady state, the dispensed volume of Apelvis is 114 liters.