How much does a box of domestic ibrutinib/ibrutinib cost?

Ibrutinib/ Ibrutinib is a targeted drug that works by inhibiting Bruton's tyrosine kinase (BTK), which is part of a key signaling pathway in certain cancers, especially B-cell leukemias and lymphomas. By blocking this pathway, ibrutinib triggers the death of cancer cells. Imbruvica can be used to treat: Waldenstrom's macroglobulinemia (WM)/chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL); ibrutinib can also be used to treat chronic graft-versus-host disease (cGVHD).

The original drug of ibrutinib is available in the form of capsules in China and was approved for marketing by the State Food and Drug Administration in August 2017. It is used to treat related hematological diseases such as leukemia and lymphoma. The launch of this drug provides new treatment options for domestic patients, helping to improve treatment effects and quality of life. Patients can obtain a prescription for ibrutinib under the advice of a doctor, and purchase and use this drug at qualified medical institutions. At the same time, ibrutinib should also pay attention to the side effects and reimbursement policy of the drug in order to provide better treatment. With the continuous improvement of medical insurance policies, ibrutinib has also entered the reimbursement list of Class B medical insurance, but only patients who meet the indication conditions will be reimbursed.

The original drug on the domestic market is sold under the name of ibrutinib capsules. The common format is 140mg*90 capsules. Each box sells for about 10,000 yuan. The price of domestic generic drugs is still unclear. The price of overseas original drugs with the same specifications may exceed US$10,000, which is relatively expensive. Ibrutinib generics are also sold overseas, and each box may only cost a few hundred to 1,000 yuan (the price may fluctuate due to exchange rates). The ingredients of the two drugs are the same, and the price is relatively affordable.