What are the possible adverse reactions of taking dacomitinib/dacomitinib?

Dacomitinib (Dacomitinib) is an anti-tumor drug used to treat non-small cell lung cancer (NSCLC). Although it is effective against tumors, it may also cause some side effects. When using dacomitinib to treat non-small cell lung cancer, doctors need to pay close attention to the patient's response and adjust the dose or change drugs in a timely manner to ensure the safety and effectiveness of the treatment. The main side effects of dacomitinib are described in detail below:

1. Skin reaction: One of the most common side effects of dacomitinib is rash. Rashes usually appear on the face, back and other parts of the body, and may cause discomfort such as itching, redness, swelling, and scaling. Sometimes, the rash may progress into blisters, herpes, or ulcers. In addition, dry, peeling, and sore skin on the palms and soles of the feet are possible side effects.

2. Gastrointestinal reactions: Dacomitinib may also cause gastrointestinal reactions such as diarrhea, nausea, vomiting and loss of appetite. These side effects may have an impact on the patient's quality of life.

3. Oral problems: Dacomitinib can also cause problems such as oral ulcers, dry mouth, and oral inflammation. Patients may experience oral discomfort and difficulty swallowing.

4. Fatigue and decreased physical strength: Some patients will feel fatigue and decreased physical strength after taking dacomitinib. This may affect daily life and work.

5. Hypertension: Dacomitinib may cause the patient's blood pressure to increase. During treatment, doctors will closely monitor the patient's blood pressure and make adjustments as needed.

6. Respiratory system problems: Dacomitinib may also cause respiratory system problems, such as pneumonia and interstitial lung disease. These side effects can be serious and require prompt notification and treatment by your doctor.

7. Other side effects: Dacomitinib may also cause other adverse reactions such as headache, joint pain, abnormal liver function, etc.