Are giritinib fumarate tablets sold in domestic hospitals?

Gilteritinib Fumarate tablets are an oral drug mainly used to treat FLT3 mutation-positive acute myeloid leukemia (AML). As a targeted therapy drug, it blocks the proliferation and survival of leukemia cells by inhibiting the FLT3 receptor kinase, thereby prolonging the survival of patients and improving the effectiveness of treatment.

Although giritinib has been launched in the domestic market, unfortunately, it has not yet been included in the scope of medical insurance, making its domestic price high, with a single bottle costing more than 20,000 yuan. For more specific pricing, please check directly with your local hospital or pharmacy. Compared with domestic ones, the prices of foreign generic drugs are more affordable. In particular, the price of generic drugs produced in Laos is only about two to three thousand yuan, which is far lower than that in the domestic market. It is worth mentioning that the ingredients of these generic drugs are highly consistent with those of domestic original drugs.

The main ingredient of Giritinib Fumarate Tablets is giritinib, which exists in the form of fumaric acid. This medication is usually available in tablet form for patients to take orally.

Giritinib is a tyrosine kinase inhibitor that mainly works by inhibiting the activity of FLT3 receptor kinase. FLT3 is an important cell surface receptor that is frequently mutated in AML, leading to abnormal proliferation and survival of AML cells. Giritinib can block the FLT3 signaling pathway and inhibit the proliferation and survival of AML cells, thereby achieving the therapeutic effect of AML.

Giritinib fumarate tablets are mainly used to treat FLT3 mutation-positive relapsed or refractory AML. This type of AML is often insensitive to traditional chemotherapy, so specific targeted therapies are needed to control disease progression.

When using giritinib fumarate tablets, patients need to strictly follow the doctor's recommendations and prescriptions. Typically, it is recommended to take it after a meal and follow instructions for dosage adjustment and dosing schedule. At the same time, patients should undergo regular blood tests and clinical evaluations to monitor treatment effects and the occurrence of adverse reactions.

In general, gilitinib fumarate tablets, as a targeted therapy, have important clinical significance in the treatment of FLT3 mutation-positive AML patients. Patients should pay close attention to the doctor's instructions during use and conduct regular follow-up visits and examinations to ensure the effectiveness and safety of the treatment.