Domestic medical insurance price of mitotane in 2024

Mitotane (Mitotane) is a drug used to treat adrenocortical adenomas and is also used to treat adrenocortical cancer. It belongs to a class of drugs called ketosterols, which work by inhibiting the function of the adrenal cortex. Mitotan (mitotane) acts on the adrenal cortex in a variety of ways, including inhibiting the synthesis and secretion of adrenocortical hormones, resulting in toxic effects on tumor cells.

Although Mitotane has been marketed in China, it has not yet been included in the scope of medical insurance. Therefore, it is still difficult for patients to purchase this drug in domestic hospitals. For more information, ask your local hospital pharmacy. Abroad, Mitotane has two versions: original drug and generic version. The original drugs are mainly European versions, priced as high as more than 9,000 yuan. In comparison, generic drugs, especially the version produced in Laos, are more affordable at about more than 3,000 yuan, and their pharmaceutical ingredients are basically the same as the original drugs.

Mitotane is mainly used to treat primary adrenocortical cancer or metastatic adrenocortical cancer. It may also be used to treatCushing syndrome, a disorder caused by excess adrenocortical hormones.

Mitotane is usually taken by mouth, and the dosage will be based on the patient's specific condition and the advice of the doctor. When initiating treatment, it is common to start with a lower dose and gradually increase the dose until optimal effectiveness is achieved. During treatment, doctors will regularly monitor the patient's tumor indicators and adrenocortical hormone levels to ensure treatment effectiveness and adjust dosage.

Mitotane may cause a series of adverse reactions, including but not limited to nausea, vomiting, diarrhea, loss of appetite, fatigue, dizziness, rash and jaundice. Serious adverse reactions may include abnormal liver function, thrombocytopenia, and allergic reactions. Therefore, patients should be monitored regularly and pay close attention to the occurrence of adverse reactions during the use of mitotane.

While taking Mitotane , patients should avoid alcohol and other drugs that may affect liver function. At the same time, female patients should take effective contraceptive measures during treatment because mitotane may cause damage to the fetus.