Detailed explanation of dacomitinib/dacomitinib dosage forms and dosages

Dacomitinib/Dacomitinib, as a drug approved by the U.S. Food and Drug Administration (FDA), is specifically designed to detect EGFR RGQ through specific diagnostic tests (such as therascreen EGFR RGQ PCR kit, Cobas EGFR mutation detection v2, etc.) are confirmed to be first-line treatment for patients with metastatic non-small cell lung cancer (NSCLC) who are positive for EGFR exon 19 deletion (DELL9) or exon 21 (L858R) substitution mutation. Dacomitinib is one of the highly regarded treatment options for treatment-first NSCLC patients with EGFR activating mutations and has even been designated an orphan drug by the FDA for this condition.

When talking about dacomitinib strengths, the main concerns are the dose per tablet and the number of tablets per packaging unit (such as a box or bottle). Common strengths of dacomitinib on the market include 15 mg, 30 mg and 45 mg tablets, and are usually sold in packages of 30 tablets per box. This specification design fully considers the patient's medication convenience and drug storage and carrying needs.

Different strengths of dacomitinib are suitable for different patient groups and treatment options. The doctor will comprehensively consider the severity of the patient's illness, physical condition and the desired treatment effect, and recommend the most suitable specifications and dosage for the patient. Therefore, patients must strictly follow medical instructions when purchasing and using dacomitinib to ensure the safety and effectiveness of treatment.

In addition, the selling prices of different specifications of dacomitinib on the market are also different. For example, the price of a domestically sold original drug of 15 mg per tablet and 30 tablets per box may be as high as more than RMB 1,000; while overseas, the price of an original drug of 45 mg per tablet and 30 tablets per box may exceed RMB 20,000. At the same time, the price of generic drugs produced in Laos with the same specifications may be around RMB 800 (please note that the price may change due to exchange rate fluctuations).