How much does tucatinib/tucatinib cost per month?

Tucatinib is available as 50 and 150 mg tablets under the brand name Tukysa. Tucatinib is indicated for the treatment of adult patients with trastuzumab and capecitabine diagnosed with advanced unresectable or metastatic HER2-positive breast cancer, this includes patients with brain metastases and those who have received one or more antiHER2-based regimens in the metastatic setting. Tucatinib is also indicated in combination with trastuzumab for the treatment of adult patients with RAS wild-type HER2-positive unresectable or metastatic colorectal cancer who have progressed following fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy.

The active substance in tucatinibtucatinib is a type of cancer drug called a tyrosine kinase inhibitor. It attaches to the HER2 protein on cancer cells, thus blocking its effects. Because HER2 helps cancer cells grow and divide, blocking it helps control cancer growth by stopping these cells from growing and causing them to die. The recommended dose of tucatinib is 300 mg orally twice daily until disease progression or unacceptable toxicity.

TucatinibEach box contains about30 tablets, or about 60 tablets. Taking the original drug with toggle plate as an example, the price per box of 150 mg 60 tablets may be as high as more than 70,000 yuan (the price may fluctuate due to exchange rate changes). If the patient has been taking the drug and has no tolerance, the price may be more than 70,000 yuan for one month's use. However, if we take overseas Bangladeshi generic drugs as an example, the price of each box of 150mg 30 tablets is about more than 4,000 yuan (the price may fluctuate due to exchange rate changes). The price for a patient's use for one month may be less than 10,000 yuan, which is relatively cheaper than the price of the original drug.