How much does tucatinib/tucatinib treatment cost per month?

Tucatinib/Tucatinib, brand name Tukysa, is available in 50 mg and 150 mg tablets. The drug is specifically indicated for the treatment of adult patients with advanced unresectable or metastatic HER2-positive breast cancer, with or without brain metastases, and those who have received one or more anti-HER2-based treatment regimens in the metastatic setting. Tucatinib is also recommended in combination with trastuzumab for the treatment of adult patients with RAS wild-type, HER2-positive unresectable or metastatic colorectal cancer, especially those whose disease has progressed despite chemotherapy with fluoropyrimidine, oxaliplatin, and irinotecan.

The main component of TucatinibTucatinib is a tyrosine kinase inhibitor that can bind to the HER2 protein on the surface of cancer cells, thereby blocking its role in promoting the growth and division of cancer cells. In this way, tucatinib helps control cancer growth. The recommended dose is 300 mg orally administered twice daily until disease progression or drug toxicity reaches unacceptable levels.

Regarding the packaging of the drug, tucatinib usually contains about30 or 60 tablets per box. Taking the European version of the original drug as an example, a box of 60 tablets of 150 mg each may cost more than 70,000 yuan. If the patient continues to use the drug and does not develop drug resistance, then according to a rough estimate, the cost of treatment for a month may exceed 70,000 yuan. However, if you choose to use overseas Bangladeshi generic drugs, the price of 30 tablets per box and 150 mg per tablet is about more than 4,000 yuan, and the patient's monthly treatment cost may be less than 10,000 yuan. Compared with original drugs, the price of generic drugs is obviously more affordable.